Infections in Children with Asthma
Abdullah Abdulrahman Al Shimemeri
Issue:
Volume 2, Issue 1, February 2014
Pages:
1-5
Received:
27 November 2013
Published:
30 January 2014
Abstract: Asthma is one of the most common chronic disorders in childhood. Asthma symptoms normally find in first three years of a life when the growth and remodeling of lungs is at maximum pace. There is always a common concern regarding different forms of asthma and how to cure them. Studies showed us in US about 20 million people are suffering from asthma and out of which 9 millions are children. Globally around 70% of asthmatic children are suffering from Wheeze which is mostly a symptom of viral infection. This is also one of the global burdens due to respiratory viral infections imposed by asthma. The various types of infections include rhinovirus infections which plays a crucial role in asthma development; respiratory syncytial virus which cause lower respiratory tract infection such as bronchiolitis; influenza and par- influenza viruses; pertussis, one of the major reason of death for children below 3 months of age; epiglottitis; bronchiolitis which effects mainly children below age of 2; and pneumonia caused by bacteria, fungi, parasites or due to virus. In this article we will shed some light on the relationship of chest infections with asthma and how they impact the course of asthma disease in children. The most important factor is how several vitamins like Vitamin D plays a crucial role for asthma patients. General studies show prevention and long term control is major key in stopping asthma attacks. There are various medications available to avoid asthma attacks but it generally depends upon the patient’s symptoms, age and the various triggering factors. Further we will see how a balanced diet helps like pro-biotic supplements, bacterial derived product, OM-85 etc helps in controlling asthma infections.
Abstract: Asthma is one of the most common chronic disorders in childhood. Asthma symptoms normally find in first three years of a life when the growth and remodeling of lungs is at maximum pace. There is always a common concern regarding different forms of asthma and how to cure them. Studies showed us in US about 20 million people are suffering from asthm...
Show More
Serum Calprotectin Level for Diagnosis and detection of Disease Activity in Rheumatoid Arthritis
Nanees Adel,
Marcel William,
Reham Al Swaff,
Sherin Hassan
Issue:
Volume 2, Issue 1, February 2014
Pages:
6-10
Received:
9 March 2014
Published:
30 March 2014
Abstract: Background: Early diagnosis of rheumatoid arthritis and timely detection of progression are global challenges. However, lack of sensitivity and imprecision of the currently available biomarkers have impaired the ability to implement potentially effective therapies in a timely manner. The present study aimed to evaluate the clinical utility of serum calprotectin in diagnosis as well as assessment of rheumatoid arthritis activity. Methods: serum calprotectin levels were measured in 60 Egyptian patients with rheumatoid arthritis (35 patients with active rheumatoid arthritis vs. 25 patients with quiescent disease) and 20 healthy subjects who served as a control group. Results: Serum calprotectin showed a highly significant elevation in patients with rheumatoid arthritis. Moreover, its level showed a highly significant increase during disease activity. Significant positive correlations were found between serum calprotectin and other markers of disease activity (ESR, CRP, WBCs, and platelets). Serum calprotectin at a cut- off level of 450 ng /mL, had 75% sensitivity &90% specificity for diagnosis of rheumatoid arthritis. Optimum cut-off level of calprotectin for prediction of disease activity was 950 ng /mL with 80% sensitivity, 76% specificity. Conclusion: serum calprotectin is a promising marker for diagnosis and monitoring of disease activity in patients with rheumatoid arthritis.
Abstract: Background: Early diagnosis of rheumatoid arthritis and timely detection of progression are global challenges. However, lack of sensitivity and imprecision of the currently available biomarkers have impaired the ability to implement potentially effective therapies in a timely manner. The present study aimed to evaluate the clinical utility of serum...
Show More
