Volume 3, Issue 3, June 2015, Page: 42-46
Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior
Magdy Abdullah Sayedelahl, Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Naser Nagib Nasr, Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Mahmoud Hamed Akr, Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
Dina Sayed Sheha, Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Tahany Mohamed Rabie, Department of Otorhinolaryngology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Received: Jun. 8, 2015;       Accepted: Jun. 18, 2015;       Published: Jul. 2, 2015
DOI: 10.11648/j.iji.20150303.13      View  4611      Downloads  119
Background: A randomized single-blinded study including 50 patients with allergic rhinitis. Objective: To evaluate and compare the efficacy of subcutaneous versus sublingual immunotherapy in treatment of allergic rhinitis. Materials and methods: Patients divided into Group A: twenty patients received subcutaneous immunotherapy and group B: twenty patients received sublingual immunotherapy for twelve months. We assessed skin prick test, symptom score and medication use, quality of life and nasal smear eosinophilic count before and after treatment. Results: In group A, clinical improvement was achieved in 100% of monosensitised and 62.5% of polysensitised patients, while in group B 100% of monosensitised and 60% of of polysensitised patients exhibited clinical improvement. Conclusion: The subcutaneous and sublingual routes of immunotherapy have similar efficacy.
Allergen Specific Immunotherapy, SCIT, SLIT, Allergic Rhinitis, Skin Prick Test, Nasal Smear Eosinophilia, Clinical Improvement
To cite this article
Magdy Abdullah Sayedelahl, Naser Nagib Nasr, Mahmoud Hamed Akr, Dina Sayed Sheha, Tahany Mohamed Rabie, Subcutaneous versus Sublingual Immunotherapy for Allergic Rhinitis therapy: Which Is Superior, International Journal of Immunology. Vol. 3, No. 3, 2015, pp. 42-46. doi: 10.11648/j.iji.20150303.13
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